Clinical Considerations for Dengue Virus Infection

Official Message No.:111492-9-6-2022-PHUP
Contact Info: George |
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Dengue is endemic in many popular travel destinations for U.S. travelers, such as the Caribbean. The Centers for Disease Control and Prevention (CDC) is monitoring ongoing dengue outbreaks occurring in several regions around the world. Because most dengue cases reported in the continental United States occur in travelers, CDC is advising clinicians to consider dengue in patients with a febrile illness who have traveled to dengue-endemic areas in the 2 weeks before symptom onset. 

Please see the attached “Clinical Considerations for Dengue Virus Infection” from CDC regarding diagnosis and treatment of dengue virus.

Reported dengue cases in New Jersey for 2020-2021 were much lower than prior to COVID-19 owing to a sharp decrease in international travel. In the 3 years prior to the COVID-19 pandemic, there were an average of 39 travel-associated cases of dengue reported per year in New Jersey, including 73 cases in 2019. The number of travel-associated dengue cases is highly dependent on travel patterns and dengue transmission levels in the destination countries.

International travel has increased this summer and several outbreaks of dengue have been reported in many countries throughout the Americas and in Asia and the Pacific Islands particularly. Nationally, 311 dengue cases have been reported from US states, all travel-associated except for five locally acquired cases reported in Florida (provisional data as of August 31st). As of September 2nd, there have been 9 reported dengue cases in New Jersey this year with several reports still under investigation.  All 9 cases are travel-associated, with cases reporting travel to Cuba (n=2), Ecuador (n=2), El Salvador (n=2), India (n=2), and the Dominican Republic (n=1).

All dengue cases are reportable to the local health department where the patient resides, but it is particularly important to report if someone with dengue has not traveled to an area where dengue is circulating. Healthcare providers are asked to remind patients returning from destinations where dengue Is circulating to “Track when You’re Back” and avoid mosquito bites for 3 weeks after returning to New Jersey, to prevent potential introduction of the virus into local mosquito populations.


CDC Travel Health Notices

CDC dengue page for healthcare providers

CDC Dengue Statistics and Maps – 2022

NJDOH Mosquito-borne Disease: Track when You’re Back

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